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Pertechnetate

Pertechnetate. More... A gamma-emitting radionuclide imaging agent used for the diagnosis of diseases in many tissues, particularly in the gastrointestinal system, cardiovascular and cerebral circulation, brain, thyroid, and joints 99m-pertechnetate is a radioactive tracer with 4-6 h of half-life, that can be administered i.v. and electively trapped by the thyroid gland and therefore used to obtain a true thyroid scan. Thyroid scintigraphy based on 99m-pertechnetate administration is an easy and safe exam, that is helpful in identifying the etiology of the hyperthyroidism In particular cases a RAIU can be still performed Tc-99m pertechnetate (Na + 99m Tc O 4-) is one of the technetium radiopharmaceuticals used in imaging of thyroid, colon, bladder and stomach. Technetium (99m Tc) has eight oxidation states 6, from -1 to +7; specifically, the oxidation state of technetium in the pertechnetate anion (99m TcO 4-) is +7 Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa, and choroid plexus. However, in contrast to the iodide ion, the pertechnetate ion is released unchanged from the thyroid gland Pertechnetate sind eine Stoffgruppe von chemischen Verbindungen, welche das Pertechnetat-Anion TcO 4 − beinhalten. Sie sind die Salze der Pertechnetiumsäure HTcO

Sodium pertechnetate is the inorganic compound with the formula NaTcO4. This colourless salt contains the pertechnetate anion, [TcO4]−. The radioactive 99mTcO4− anion is an important radiopharmaceutical for diagnostic use. The advantages to 99mTc include its short half-life of 6 hours and the low radiation exposure to the patient, which allow a patient to be injected with activities of more than 30 millicuries. NamTcO4] is a precursor to a variety of derivatives that are used to image. Pertechnetate concentrates in the thyroid gland, salivary glands, gastric mucosa and choroid plexus. After intravenous administration, it equilibrates with the extracellular space. Following the administration of Sodium Pertechnetate Tc-99m as an eye drop, the drug mixes with tears within the conjunctival space

Le pertechnétate de sodium est un composé chimique de formule Na Tc O 4. Sous la forme de Na 99m Tc O 4 (obtenu en sortie d'un générateur de technétium 99m ), il est utilisé en radiopharmacie, soit directement (en imagerie thyroïdienne ou en imagerie cérébrale lorsque la barrière hémato-encéphalique est déficiente ), soit comme précurseur مسح الغدّة الدّرقيّة بالنظائر المشعة (Radioactive thyroid scan) امتصاص اليود المشعّ داخل الغدّة الدّرقيّة (Radioactive Iodine Uptake - RAIU). يتم إجراء هذه الاختبارات عن طريق بلع كبسولة تحتوي على مادة اليود المشعّ ، أو بواسطة حقن التكنيشيوم بيرتكنيتات (Tc - 99m Pertechnetate)

Pertechnetate O4Tc- - PubChe

Pertechnetate - an overview ScienceDirect Topic

  1. Conclusion: The 99m Tc-pertechnetate scintigraphy is a simple and feasible tool to predict effectiveness of low activity ¹³¹I thyroid to ablate thyroid remnants in patients with DTC. Keywords: Differentiated thyroid carcinoma; Radioiodine; Radionuclide imaging; Sodium pertechnetate Tc 99m
  2. Spot sodium pertechnetate eluate on the Whatman 3 MM strip. 2. Develop the strip in Acetone. Count each half of the strip in a scintillation well. 3. Free sodium pertechnetate is located at solvent front (top); Hydrolyzed reduced is located at the origin (bottom). 4. Calculate: % free Tc-99m = top counts/(bottom counts + top counts) x 100. 5
  3. ations
  4. Find patient medical information for sodium pertechnetate Tc-99m intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings
  5. CT or MR enterography and 99m Tc-sodium pertechnetate scintigraphy can provide complementary information that enables specific diagnosis and accurate assessment of disease extent
  6. , and the radioiodide can be ad
  7. ation remediation of nuclear waste. Herein, we report a cationic metal-organic framework (TJNU-216, TJNU = Tianjin Normal University), with ultra-high selectivity in trapping perrhenate/pertechnetate in the presence of a large excess of SO 4 2− (20 000 times) or NO 3 − (300 times), and the.

Tc-99m pertechnetate Radiology Reference Article

Cooperative halide, perrhenate anion-sodium cation binding and pertechnetate extraction and transport by a novel tripodal tris(amido benzo-15-crown-5) ligan Technetium-99m (99mTc) is a radionuclide isotope that is used primarily for imaging and diagnostic purposes. [1] It was isolated in 1938 from molybdenum-99 (Mo-99) decay and is the most common radioactive isotope tracer used for SPECT (single-photon emission computerized tomography) imaging of the brain, bones, lungs, kidneys, thyroid, heart. The main reason is that although 99m Tc-pertechnetate and iodine form monovalent anions, have similar physical and chemical properties and can be accumulated by sodium iodide symporter (Na+/I-symporter) located in the membrane of thyroid cells, 99m Tc-pertechnetate cannot further participate in thyroid hormone synthesis after entering thyroid. Thyroid uptake of 99m Tc-pertechnetate is a useful way to determine the cause of thyrotoxicosis. In daily clinical practice, 99m Tc-pertechnetate uptake is used to discriminate between Graves' disease and painless thyroiditis when clinical information is not enough to make the distinction. However, since the optimal cutoff value of 99m Tc-pertechnetate uptake has not yet been elucidated, our. Most commonly, at our institution, thyroid scintigraphy is performed with technetium-99m pertechnetate. Imaging begins 15 minutes after intravenous injection of 10 mCi (370 MBq) of Tc-99m pertechnetate. A pinhole collimator with a 3.5-mm aperture is used as well as an energy setting of 140 keV photopeak for Tc-99m

Technetium Tc-99m pertechnetate: Uses, Interactions

pertechnetate. The 99Mo activity remaining on the column continues to decay, generating more 99mTc activity. A generator has a useful life of two weeks, however weekly replacement is the norm to supply the required amount of technetium activity for daily needs. The generator eluate consists of both 99mTc and 99Tc as pertechnetate. The chemical. Further, the mobile pertechnetate ion is easily fixed in plants into less mobile Tc organics, oxides, or sulfides. Plant-fixed Tc is likely one of the key sources of Tc radiation to humans. Once in the body, pertechnetate is readily transferred to the bloodstream with high efficiency by the intestines and lungs The Technetium Tc 99m labeling reactions involved in preparing the agent depend on maintaining the stannous ion in the reduced state. Any oxidant present in the sodium pertechnetate Tc 99m supply may, thus, adversely affect the quality of the radiopharmaceutical. Hence, sodium pertechnetate Tc 99m containing oxidants should not be employed

The pertechnetate ion could be used as to prevent anodic corrosion in steel. Before the element was found, many of the properties of element 43 were predicted by Dmitri Mendeleev. Mendeleev saw a gap in his periodic table. He named the element in the gap ekamanganese modifier. Le technétium est l' élément chimique de numéro atomique 43, de symbole Tc. Le technétium est l'élément le plus léger ne possédant pas d' isotope stable. Les propriétés chimiques de ce métal de transition radioactif de couleur gris métallique, rarement présent dans la nature, sont intermédiaires entre celles du rhénium. This approval allows RadioGenix System to produce sodium pertechnetate Tc-99m injection to be injected intravenously, instilled into the bladder or eye, or used with other FDA approved imaging drugs to examine specific tissues and organs, concluded the company Blood vessel diseases—Sodium Pertechnetate Tc 99m Blood vessel diseases of the brain—Ammonia N 13, Iofetamine I 123, Technetium Tc 99m Bicisate, Technetium Tc 99m Exametazime, Xenon Xe 133 Bone diseases—Sodium Fluoride F 18, Technetium Tc 99m Medronate, Technetium Tc 99m Oxidronate, Technetium Tc 99m Pyrophosphate, Technetium Tc 99m (Pyro. Technetium pertechnetate and Iodine based radionuclides such as . 131. Iodine and . 123. Iodine. 99m. Tc- Pertechnetate. is the chemical form of . 99m. Tc eluted from the . 99. molybdenum/ 99m. Tc generators. 'm' in Tc-99m indicates metastable or an excited state that comes to a stable state 'Tc-99' by isomeric transition

2]+ from Pertechnetate Michael Benz, Henrik Braband, Paul Schmutz, Jonathan Halter and Roger Alberto Department of Chemistry, University of Zürich, Winterthurerstr. 190, CH-8057 Zürich Switzerland Supporting Information Table of Contents 1 Experimental Section 1.1 General procedures for the preparation of [99Tc(arene) 2](PF6) 1.1.1 [99Tc(benzene chemical form of pertechnetate ion (i.e., TcO4-). Pertechnetate distributes throughout the vasculature and interstitial fluid, and con-centrates primarily in the stomach, intestinal tract, urinary tract, thyroid gland, and sali-vary glands. A second radiochemical impu-rity associated with some Tc-99m radio-pharmaceuticals is insoluble Tc-99m in th

Technetium-99m sodium pertechnetate Technetium-99m sodium pertechnetate is used in SPECT imaging of the brain including thyroid and salivary gland imaging. Also, used in angiography and urinary bladder imaging. Technetium-99m succimer Used to evaluate renal parenchymal disorders. Technetium-99m sulfur colloi Technetium-99m pertechnetate has a short half-life (6 hours) but higher background levels than radioiodine. It is the preferred agent when the patient has recently received thyroid-blocking agents (such as iodinated contrast media). Breastfeeding recommendations regarding Tc-99m per-technetate depend on the dose administered, as it does hav The most useful method of diagnosis is with a technetium-99m pertechnetate scan, which is dependent on uptake of the isotope in heterotopic tissue. Management is by surgical resection This study demonstrated that the TGs were invisible on [99m Tc]pertechnetate SPECT/CT images, and that [18 F]FDG and [11 C]methionine uptakes in the TGs were not undistinguishable from the uptake in the tubal tonsils.To our knowledge, this is the first report evaluating the uptake of radiopharmaceuticals in the TGs other than PSMA ligands However, technetium-99m (99m Tc) pertechnetate scintigraphy is useful for diagnosis of WT[19, 20]. Hence, we additionally hypothesized that the candidate for CNB can be further reduced by screening WT with 99m Tc pertechnetate scintigraphy among tumors with a low ADC value

Sodium pertechnetate - Wikipedi

  1. GI bleeding is a common presenting symptom in children and adults. The most useful diagnostic tool in cases with bleeding is the technetium-99m pertechnetate scan (Meckel's scan). Obstructive symptoms are another common presenting symptom and may be caused by several mechanisms, including intussusception
  2. The TechneLite ® generator is a source of sodium pertechnetate Tc 99m for use in the preparation of FDA-approved diagnostic radiopharmaceuticals, as described in the labeling of these diagnostic radiopharmaceutical kits. Sodium Pertechnetate Tc 99m Injection is used IN ADULTS as an agent for: Thyroid Imaging. Salivary Gland Imaging
  3. Activity in the stomach on GI bleeding scintigraphy may represent free Tc-99m pertechnetate. In this case there were two clues that the stomach activity was not due to free pertechnetate. First, the initial activity appears to be pooling in the fundus of the stomach rather than accumulating within the wall of the stomach

pertechnetate escapes the conjunctival space in the tears. While the major part of the pertechnetate escapes within a few minutes of normal drainage and tearing, it has been documented that there is some degree of transconjunctival absorption with a fractional turnover rate of .015/min. in normal individuals, .021/min. in patients without an Pertechnetate thyroid scan: This uses sodium pertechnetate - 99m TCO 4 - instead of radioactive iodine. The advantage of pertechnetate scans is that they can be done immediately, whereas the radioactive iodine scans take 4-6 hours. However, they are less sensitive than radioactive iodine scans Pertechnetate Tc 99m affects fertility in males or females. Pregnancy Category C . Animal reproductive studies have not been conducted with Sodium Pertechnetate Tc 99m. It is also not known whether Sodium Pertechnetate Tc 99m can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium Pertechnetate T DESCRIPTION: Sodium Pertechnetate Tc 99m Injection, as eluted according to the elution instructions with Lantheus Medical Imaging, Inc. TECHNELITE ®, Technetium Tc 99m Generator, is in Sodium Chloride 0.9% as a sterile, non-pyrogenic, diagnostic radiopharmaceutical suitable for intravenous injection and direct instillation.The pH is 4.5-7.5. The eluate should be clear, colorless, and free. pertechnetate is trapped by thyroid follicular cells. 123 I-Iodide is both trapped and organified by thyroid follicular cells. 1.1 Assessment of functionality of thyroid nodules. 1.2 Assessment of goitre including hyperthyroid goitre. 1.3 Assessment of uptake function prior to radio-iodine treatment 1.4 Assessment of ectopic thyroid tissue

A Technetium Phyrophosphate Scintigraphy or PYP Scan is a type of nuclear scan that is used along with blood and urine tests to diagnose Transthyretin (TT.. The efficiency of pertechnetate extraction correlates with the lipophilicity of the guanidinium compounds. 1:1 complex formation in the organic phase was observed. The influence of hydroxide, chloride and bicarbonate on the pertechnetate extraction has been investigated. Pertechnetate is extracted with great preference over OH −, Cl − and. When sodium pertechnetate ( Tc) is used, 40-150 MBq are injected and neck and thorax images are acquired 30 minutes later. Then 200 to 700 MBq of technetium (99m. Tc) sestamibi are injected and a second acquisition of images is acquired 10 minutes later

INDICATIONS & USAGE SECTION for RadioGenix System 1

  1. Sestamibi scan and pertechnetate thyroid scan with SPECT or SPECT/CT neck Usually Appropriate ☢☢☢ Venous sampling parathyroid . May Be Appropriate Varies ; MRI neck with IV contrast . May Be Appropriate O MRI neck without and with IV contrast : May OBe Appropriate CT neck with IV contrast . May Be Appropriate
  2. Tc-99m Sodium Pertechnetate (Thyroid Gland Scan, MUGA scan) Technetium (99mTc) Sodium Pertechnetate can used in thyroid, colon, bladder and stomach imaging. MUGA study is one of the major uses of 99mTc Sodium Pertechnetate, which can assess regional and global wall motion, cardiac chamber size and morphology, and also regional and global wall.
  3. e the base line labeling of in-house made kits such as that of DTPA, elution yields. The column was washed with 100 mL L,L-ECD and MIBI
  4. The objective of this study was the utilization of three different biochars for pertechnetate removal from aqueous solutions. Biochars were prepared by slow pyrolysis from different feedstocks, characterized by BET, acid-base titration, SEM, XRD and FTIR and tested for their pertechnetate sorption using batch and dynamic techniques. Effect of various physico-chemical parameters such as.
  5. g the long-term challenge of TcO 4- segregation under extreme conditions of super acidity and basicity, strong irradiation field, and high ionic.

Technetium-99m pertechnetate scan in a 12-year-old boy who presented with intermittent dull abdominal pain and a mild iron deficiency anemia. On the present occasion, the pain appeared more severe and was associated with occasional vomiting; thus, the child was hospitalized. This 90-minute delayed image shows focal activity in the mid abdomen As one of most problematic radionuclides, technetium-99, mainly in the form of anionic pertechnetate (TcO 4 −), exhibits high environmental mobility, long half-life, and radioactive hazard.Due to low charge density and high hydrophobicity for this tetrahedral anion, it is extremely difficult to recognize it in water scintigraphy with tc-99m pertechnetate revealed a diffusely enlarged thyroid gland with homogenous uptake, suggesting diffuse toxic goiter. 26. retrosternal goiter 27. the activity uptake decreases with variable sizes in hypothyroidism 28. hot nodule cold nodule 29 Technetium, chemically similar to rhenium (atomic number 75), exists in oxidation states of +7, +6, and +4 in compounds such as potassium pertechnetate, KTcO 4, technetium chloride, TcCl 6, and technetium sulfide, TcS 2, respectively. Compounds are known in all formal oxidation states from −1 to +7

Pertechnétate de sodium — Wikipédi

<p>We characterized the scintigraphic and sonographic appearance of the thyroid gland in clinically normal horses to establish the value of these modalities for assessment of the thyroid gland in this species. Horses were divided into two age groups. One group consisted of eight horses between 3 and 10 years of age and the other of seven horses between 11 and 20 years of age. Total T<sub>4. Sodium Pertechnetate Tc 99m Injection is a radioactive diagnostic agent and can be used in the preparation of FDA-approved diagnostic radiopharmaceuticals. Sodium Pertechnetate Tc 99m Injection is. Technetium Tc 99m Sodium Pertechnetate - Last updated on June 7, 2021 All rights owned and reserved by Memorial Sloan Kettering Cancer Center. Educational Resources. Log in to print or send this list to your patient and save lists of resources you use frequently

تصوير الغدة الدرقية: طريقة إجراء الفحص وتحليل النتائ

pertechnetate ( plural pertechnetates ) ( inorganic chemistry) The univalent technetium anion TcO 4-; any salt containing this anion Sodium Pertechnetate (99Tc) Injection Generator: 99mTc From Neutron-activation 99Mo v 99mTc From Fission 99Mo. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government Structure, properties, spectra, suppliers and links for: Ammonium pertechnetate

Pertechnetate definition of pertechnetate by Medical

1. J Nucl Med. 1967 May;8(5):394. Colon scanning with technetium-99m pertechnetate. Patton DD, Crenshaw RT. PMID: 6032725 [PubMed - indexed for MEDLINE Ultra-TechneKow™ DTE (Technetium Tc 99m Generator) For the Production of Sodium Pertechnetate Tc 99m Injection. DESCRIPTION. The Ultra-TechneKow™ DTE Generator is prepared with fission-produced molybdenum Mo-99 adsorbed onto alumina column shielded by lead, tungsten, or depleted uranium.This generator provides a closed system for the production of sterile metastable technetium Tc-99m. Technetium is a silvery-gray metal that tarnishes slowly in moist air. The common oxidation states of technetium are +7, +5, and +4. Under oxidizing conditions technetium (VII) will exist as the pertechnetate ion, TcO 4-. The chemistry of technetium is said to be similar to that of rhenium. Technetium dissolves in nitric acid, aqua regia, and.

Sodium pertechnetate NaO4Tc - PubChe

Radiopharmaceutical: Tc-99m pertechnetate Dose (Adult/Pediatric): Refer to Nuclear Medicine Dose Chart for radiopharmaceutical doses. Suggested pharmacologic pretreatment regimens (to be prescribed by the referring clinician, at his/her discretion) High 99m Tc-pertechnetate uptake, especially greater than 1.4%, predicted a high-risk of unsuccessful ablation. Higher 99m Tc-pertechnetate uptake was also related to prolonged hospitalization and the occurrence of radioiodine-induced thyroiditis. Conclusion The pertechnetate is collected in a shielded, evacuated sterile vial and calibrated prior to use. It is referred to as the eluate. 4. Quantitative removal of pertechnetate is attributed to the lack of affinity of pertechnetate for alumina, whereas molybdate is essentially completely and irreversibly bound to the alumina.. Technetium¾99m, in the chemical form of pertechnetate (99m TcO 4-), is also used for thyroid scintigraphy and uptake. 6-17 The similarity of volume and charge between the iodide and pertechnetate ions is the explanation for the uptake of 99m Tc-pertechnetate by the thyroid gland. 9,10 99m Tc-pertechnetate has been used worldwide to study the. Pertechnetate is excreted in breast milk, so breastfeeding women are advised to express and discard breast milk for 26 hours after injection. 5 Also, uptake of the radiotracer will be inhibited (and thus nondiagnostic scans may arise) if the patient is taking or exposed to iodine supplementation or thyroxine therapy. These are discussed in more.

Wandering Meckel&#39;s diverticulum on 99m technetium

pertechnétate — Wiktionnair

Imaging using a scintillation camera can be done after radioisotope administration (radioiodine or technetium 99m pertechnetate) to produce a graphic representation of isotope uptake. Focal areas of increased (hot) or decreased (cold) uptake help distinguish areas of possible cancer (thyroid cancers exist in < 1% of hot nodules compared with 10. Technetium-99 (chemical symbol Tc-99) is a silver-gray, radioactive metal. It occurs naturally in very small amounts in the earth's crust, but is primarily man-made. Technetium-99m is a short-lived form of Tc-99 that is used as a medical diagnostic tool 99m Tc-pertechnetate is the radiopharmaceutical of choice as it localizes to gastric mucosa. This agent's mechanism of localization is via both the parietal cells and the mucin-secreting cells of the gastric mucosa . A Meckel scan assists in localizing the abnormal tissue in preparation for surgical removal Welcome Pragati Pandey! Schelter Group Awards. Schelter Group Awards. 03.01.20 - Congratulations to Eric and the Schelter Group for receiving the Inorganic Chemistry Lectureship Award! Link. 2.29.20 Paper. Paper Accepted. 02.29.20 - We have a new paper in Chemical Communications 99mTc-Pertechnetate (99mTcO4-) has widespread clinical use in the diagnosis and evaluation of dysfunctions in many different tissues. However, despite the broad clinical application of this radionuclide, very little is known about the mechanism by which 99mTcO4- enters a cell

過テクネチウム酸塩 - Wikipedi

Les activités suivantes sont disponibles : 2, 4, 6, 8, 10, 12, 16 ou 20 GBq à calibration. Le pertechnétate ( 99m Tc) de sodium injectable est produit au moyen d'un générateur radiopharmaceutique ( 99 Mo/ 99m Tc). Le technétium ( 99m Tc) décroit en émettant des rayons gamma avec une énergie moyenne de 140 keV et une période de 6,02. The pertechnetate Tc 99m diffuses across the red blood cell membrane and is reduced by the intracellular stannous ion. The reduced technetium Tc 99m cannot diffuse out of the red blood cell. The red blood cell labeling is essentially complete within 20 minutes of sodium pertechnetate Tc 99m addition to the reaction vial

Pertechnetate Meaning - YouTub

• If imaging is required with Tc-99m pertechnetate, verify two forms of identification with patient, inject radiopharmaceutical, and wait 15 minutes before imaging. Scan • Wait 15 minutes post Tc-99m pertechnetate before imaging. Instruct the patient to remove all metal objects from neck and chest and lay supine on the imaging table Technetium 99m, widely used in nuclear medicine, is a long-lived intermediary step in the life of a technetium nucleus obtained through the decay of molybdenum 99. According to the flowchart, the emission of a beta electron leaves behind an excited nucleus, which returns to its ground state by emitting a gamma photon Technetium-99m is a metastable isotope with a half-life of six hours. Technetium-99m emits gamma rays and low energy electrons, forming technetium-99 (half-life 211,000 years). The gamma rays can be photographed using a gamma camera, and technetium-99m is used in 80 to 90 percent of all diagnostic procedures that use radioactive elements

【解答・解説】腹痛で受診した50歳代男性.有名な疾患ですが,典型例は珍しいです.|実践!画像診断Q&A|羊土社Meckel’s Diverticulum’s16: Thyroid Diseases | Pocket DentistryTechnetium and blood extravasation before gammagraphy: aGraves&#39; disease presenting as pseudotumor cerebri: a caseChallenges in Parathyroid Cancers: A Review | Journal ofThe ‘wandering’ Meckel diverticulum: an unusualGastric Duplication Cyst with Macroscopic Serosal

Technetium Tc-99m pertechnetate is also a component of other Technetium Tc-99m radiopharmaceuticals with separate AXXXX codes. Code A9512 shall not be reported with other AXXXX radiopharmaceuticals containing Technetium Tc-99m for a single nuclear medicine study. However, if 2 separat The Tc99m pertechnetate should be from a recent elution from a generator that has been previously eluted within the last 24 hours. 6. Mix by gently inverting reaction vial four to five times. Allow to react for 20 minutes with occasional mixing. 7. Re-inject the Tc99m-labeled red blood cells. They should be injected within 30 minutes o Sodium Pertechnetate Tc-99m contributes to a patient's overall long-term cumulative radiation exposure. Long-term cumulative radiation exposure is associated with an increased risk of cancer. Use the lowest dose of Sodium Pertechnetate Tc-99m necessary for imaging and ensure safe handling and preparation to protect the patient an Connolly SA, Drubach LA, Connolly LP. Meckel's diverticulitis: diagnosis with computed tomography and Tc-99m pertechnetate scintigraphy. Clin Nucl Med. 2004 Dec. 29 (12):823-4. . Sinha CK, Pallewatte A, Easty M, et al. Meckel's scan in children: a review of 183 cases referred to two paediatric surgery specialist centres over 18 years

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